IVIG is a plasma product formed by taking antibodies from about 20,000 donors and incorporating them together. The purified plasma treatment contains antibodies which are collected from the plasma of healthy donors and purified through a special process so that the therapy is safe and effective. Most of the antibodies are of the IgG class of antibodies, also called immunoglobulin G or gamma globulin. IVIG has proven effective in several immune system disorders, including nearly all autoimmune conditions.

There are differences in IVIG brand formulas that may make one product more suitable for certain conditions than another. Consideration should be given for all factors and consultation with the pharmacist is imperative. Many of these drugs are available in SubQ or infusion therapy.

Subcutaneous Immune Globulin

  • Gammagard® Liquid : Liquid : Baxter Healthcare
  • Gammaked™ : Liquid : Kedrion Biopharma
  • Gamunex®-C : Liquid : Grifols
  • Hizentra® : Liquid : CSL Behring

Intravenous Immune Globulin

  • Bivigam® : Liquid : Biotest Pharmaceuticals
  • Carimune® NF : Lyophilized : CSL Behring
  • Flebogamma® 5% DIF : Liquid : Grifols
  • Flebogamma® 10% DIF : Liquid : Grifols
  • Gammagard® S/D IgA <1 μg/mL : Lyophilized : Baxter Healthcare
  • Gammagard® Liquid : Liquid : Baxter Healthcare
  • Gammaked™ : Liquid : Kedrion Biopharma
  • Gamunex®-C : Liquid : Grifols
  • Octagam® : Liquid : Octapharma
  • Privigen® : Liquid : CSL Behring

Intramuscular Immune Globulin

  • Gamastan® SD

Hepatitis Immune Globulin

  • HepaGam B
  • HyperHep B

Advantages of IVIG therapy is that they have the potential to reduce or eliminate the need for drugs that can have serious side effects. It is the only treatment for autoimmune disease that doesn’t suppress the immune system and can be used in children whose immune systems may already suppressed. IVIG can be combined with other therapies, such as ACTH, steroids, chemotherapy, and other immunosuppressants or plasmapheresis.

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